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Drug and Therapeutics Bulletin 1995;33:23-24; doi:10.1136/dtb.1995.33323
Copyright © 1995 by the BMJ Publishing Group Ltd.

Antibiotic-induced diarrhoea

Relevant BNF section: 5.1

Nearly all antibiotics can cause diarrhoea.1 In most instances the cause of diarrhoea is not clear.2 In some, infection with Clostridium difficile is responsible; in others there is a drug-specific mechanism, such as the inactivation of lipase by tetracycline, the binding of bile acids by neomycin or the acceleration of gut transit by erythromycin. This article discusses infection with C. difficile.


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