Drug and Therapeutics Bulletin 1999;37:1-3; doi:10.1136/dtb.1999.3711
Copyright © 1999 by the BMJ Publishing Group Ltd.
Mirtazapine - another new class of antidepressant
Relevant BNF section: 4.3.1
Mirtazapine (Zispin-Organon) was introduced in 1997 as "the first noradrenergic and specific serotonergic antidepressant" (or 'NaSSA'). The manufacturer claims that mirtazapine is "effective in all types of depression", with "minimal serotonergic, anticholinergic and antiadrenergic side-effects", "low propensity for interactions", and lower likelihood of relapse during maintenance treatment than with amitriptyline. Is mirtazapine an advance on existing drugs?
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