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Drug and Therapeutics Bulletin 2005;43:85-88; doi:10.1136/dtb.2005.431185
Copyright © 2005 by the BMJ Publishing Group Ltd.

Leukotriene receptor antagonists - an update

Relevant BNF sections: 3.1, 3.3.2

Montelukast (Singulair - MSD) and zafirlukast (Accolate - AstraZeneca) are oral leukotriene receptor antagonists, licensed for the treatment of patients with asthma. In 1998, soon after their launch, we concluded that there was insufficient evidence to clearly define their place in treatment.1 Here, we reconsider their role in adults and children with asthma in the light of more recent evidence.


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