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Drug and Therapeutics Bulletin 2006;44:1-5; doi:10.1136/dtb.2006.4411
Copyright © 2006 by the BMJ Publishing Group Ltd.

New drugs for peripheral joint psoriatic arthritis

Relevant BNF section: 10.1

Up to 3% of people have psoriasis, and as many as 42% of these have an associated chronic inflammatory arthritis.1 In up to 20% of such patients, the arthritis progresses to become severe, destructive and deforming.2–5 Traditional drug treatments include NSAIDs and disease-modifying anti-rheumatic drugs (DMARDs) used for rheumatoid arthritis. {blacktriangledown}Leflunomide (Arava - Sanofi-Aventis), {blacktriangledown}etanercept (Enbrel - Wyeth) {blacktriangledown}inifliximab (Remicade - Schering-Plough) and {blacktriangledown}adalimumab (Humira - Abbott) are licensed for the treatment of patients with peripheral joint disease in psoriatic arthritis. Here we review drug therapy for such patients, concentrating on the newer agents.


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