Is there a place for {blacktriangledown}duloxetine?

doi:10.1136/dtb.2007.45429

Drug and Therapeutics Bulletin 2007;45:29-32; doi:10.1136/dtb.2007.45429

Is there a place for ${blacktriangledown}$ duloxetine?

Relevant BNF sections: 4.3.4, 6.1.5

${blacktriangledown}$ Duloxetine, a combined serotonin and norepinephrine reuptakeinhibitor, is licensed in the UK under two brand names for atotal of three different indications. It is available as Cymbalta(jointly promoted by Boehringer Ingelheim and Lilly) for thetreatment of patients with major depression, or with diabeticperipheral neuropathic pain; and as Yentreve (Lilly) for thetreatment of women with "moderate to severe" stress urinaryincontinence. Here we consider whether duloxetine has a rolein the treatment of patients with any of these conditions.