Drug and Therapeutics Bulletin 2008;46:93-96
Copyright © 2008 by the BMJ Publishing Group Ltd.
Annual 
zoledronic acid for osteoporosis
Relevant BNF section: 6.6.2
Zoledronic acid (Aclasta – Novartis) is the first bisphosphonate to be licensed in the UK as a once-yearly intravenous treatment for women with postmenopausal osteoporosis.1 Promotional materials claim that the drug "provides powerful osteoprotection with yearlong compliance", with "significant 3 year fracture reduction at all key sites". Here we consider whether zoledronic acid has a role in the treatment of women with postmenopausal osteoporosis.
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