Drospirenone in HRT?

doi:10.1136/dtb.2009.03.0011

Drug and Therapeutics Bulletin 2009;47:41-44; doi:10.1136/dtb.2009.03.0011

Drospirenone in HRT?

Relevant BNF section: 6.4.1.1

Drospirenone is a synthetic progestogen contained, with estradiol,in the hormone replacement therapy (HRT) product ${blacktriangledown}$ Angeliq (BayerSchering Pharma). This combination is licensed for the reliefof oestrogen-deficiency symptoms in women who are at least 1year postmenopausal.¹ It is also licensed for prevention ofosteoporosis in women at high risk of future fractures who areintolerant of, or have contraindications to, other medicinalproducts approved for the prevention of osteoporosis.¹ It hasalso been suggested that drospirenone may have an antihypertensiveeffect.² Here we discuss the place of this drug for women followinga natural menopause.