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Mefruside - a new diuretic

Abstract

Mefruside (Baycaron) is a sulphonamide diuretic with some structural resemblance to frusemide and the thiazides. Pharmacological and clinical studies of its action have been largely conducted in Germany where it was developed and marketed in 1968. The makers claim that the drug (a) has a significant antihypertensive effect of its own, (b) has an enhanced Na/K excretion ratio, and (c) has a sustained action with slow onset.

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