Article Text

PDF
Drug-resistant malaria: where it occurs and how to avoid it

Abstract

Drug resistance in the malaria parasites of man is of two kinds. The first is resistance to drugs which inhibit dihydrofolate reductase, proguanil (Paludrine) and pyrimethamine (Daraprim). This type occurs in all three common parasite species, Plasmodium falciparum, P. vivax and P. malariae. The second type of resistance is to the 4-aminoquinolines chloroquine and amodiaquine (Camoquin; Basoquin in the USA), and rarely to quinine, and this is known only in P. falciparum. Both types of resistance frequently coexist in falciparum infections.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.