Since digoxin was isolated in 19301 it has become the most commonly prescribed cardiac glycoside in this country. Because oral digoxin is incompletely absorbed attempts have been made to produce a better absorbed derivative. This has led to the introduction of medigoxin (β-methyl digoxin; Lanitop - Roussel) which is prepared by the methylation of digoxin. Medigoxin has been used elsewhere in Europe for some years.
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