Article Text

PDF
Triamterene

Abstract

Triamterene (2, 4, 7-triamino-6-phenyl pteridine, Dytac - SKF) is a new oral diuretic. It increases the urinary excretion of sodium, chloride and bicarbonate, but decreases the urinary loss of potassium. The diuretic effect of triamterene depends neither on carbonic anhydrase nor on antagonism of aldosterone, but appears to be due to a direct action of the drug on the distal renal tubule, reducing the reabsorption of sodium.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.