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Oral benzodiazepines as prophylaxis for epilepsy

Abstract

Intravenous diazepam is the drug of choice for the treatment of status epilepticus, but oral diazepam has been little used as a long-term prophylactic because in most patients the doses needed cause central depression with sleep and drowsiness while in others tolerance develops. Nevertheless benzodiazepines are being used in epilepsy for short-term courses or to supplement more conventional drugs. This article reviews the present position.

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