Inosine pranobex (Imunovir - Edwin Burgess) is an oral antiviral and immunomodulating drug marketed for use in herpes simplex and genital wart infections. Although it has been studied in the laboratory and clinic for 20 years1 its efficacy has been questioned repeatedly2–5. In tissue-culture the drug has weak and inconsistent antiviral effects2,6. Inosine pranobex acts against viruses partly by enhancing the host's immune response7,8. Clinical trials of acyclovir (Zovirax - Wellcome)9 have set high standards and other anti-herpes drugs should be compared with acyclovir.
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