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Dimethicone for gastrointestinal symptoms?

Abstract

Gastrointestinal symptoms such as eructation, borborygmi, flatus, abdominal distension and pain are often attributed to excess gas1 although such a relationship has been difficult to prove.2 Dimethicone is promoted as a defoaming agent for relief of abdominal pain due to retained gas and for “colic” in infants. It has been suggested that it may provide mucosal protection3 and it is included in many combined antacid preparations. It is also used to improve visibility during endoscopy. This article reviews the actions and clinical uses of dimethicone.

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