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New H2-blockers: does more choice help?

Abstract

Two new H2-receptor antagonists, famotidine (Pepcid PM - MSD), and nizatidine (Axid - Lilly) were marketed last year for the treatment of peptic ulceration. Many would feel that the existing and well-tried drugs are satisfactory. Do these latest competitors offer therapeutic advantages? Are they needed or simply ‘me-too’ drugs in a large and lucrative market?

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