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Corticosteroid-quinoline combinations in dermatology

Abstract

Combinations of a topical corticosteroid with one or more antibacterial agents are used mainly in the treatment of eczema which has become secondarily infected. As some clinicians believe that skin infection may play a part in the aetiology of seborrhoeic and discoid eczema, such combinations are often used in these two dermatoses. Eczema of all forms is often complicated by secondary bacterial or monilial infection, but this seems to be no more common in patients treated with topical corticosteroids1 than in those treated more conservatively. An exception is the widespread folliculitis or superficial moniliasis which is fairly common in patients treated with topical corticosteroids under occlusion with plastic film.

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