Article Text

PDF
Long acting diltiazem tablets

Abstract

Diltiazem is a calcium channel blocker used mainly to treat angina.1 Two manufacturers have recently introduced longer acting formulations of diltiazem, to be taken twice instead of three times a day. The elimination half-life of the drug ranges between 2 and 11 hours, longer when renal or liver function is impaired. The dosage patients need therefore varies considerably, and must often be titrated. The long acting tablets act for over 12 hours, so that the drug accumulates to reach a steady state in about 3 days.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.