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Alprostadil for erectile impotence

Abstract

A preparation of alprostadil (prostaglandin E1) plus syringe and diluent (Caverject - Upjohn) has recently been licensed in the UK for the treatment of erectile impotence by injection into the corpus cavernosum. How does it compare with papaverine, which, though unlicensed for this indication, has been the mainstay of drug treatment for impotence?

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  • Relevant BNF section: 7.4.5

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