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Anticholinestisrase enedrops in chronic simple glaucoma

Abstract

The medical control of chronic simple (open-angle) glaucoma is becoming more popular, and newer and more potent drugs have been produced to reduce the intra-ocular pressure. The anticholinesterases are one such group of drugs; they potentiate acetylcholine and increase aqueous outflow from the eye, perhaps by stimulating the ciliary muscle which pulls on the scleral spur, or by direct action on parasympathetic end-organs in the trabecular meshwork. The effect lasts many hours or even several days, thus achieving the uninterrupted control of intra-ocular pressure essential to prevent further loss of visual field.

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