Article Text

PDF
Do corticosteroids improve outcome in meningitis?
  • Relevant BNF section: BNF 5.1, 6.3.2

Abstract

Despite significant advances in prevention of meningitis through vaccination, and in improved antimicrobial treatment, the disease still kills around 340,000 people worldwide each year.1 Around 75% of these deaths occur in Africa and South East Asia and around 3% in Europe.1 The mortality rate for bacterial meningitis is 10–30% and sequelae, such as cranial nerve impairment, particularly leading to hearing loss, occur in 5–40% of patients.2 Whether adjunctive corticosteroid treatment improves the outcome in bacterial meningitis through an anti-inflammatory effect has been a long-standing controversy. Here we review the role of adjunctive corticosteroids in the management of children (aged over 1 month) and adults with bacterial or tuberculous meningitis.

Statistics from Altmetric.com

  • Relevant BNF section: BNF 5.1, 6.3.2

View Full Text

Footnotes

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.