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Declinax - a new hypotensive agent

Abstract

Debrisoquine (Declinax - Roche) is another hypotensive agent which specifically inhibits the release of noradrenaline from stimulated adrenergic nerves, as do guanethidine (Ismelin - Ciba) and bethanidine (Esbatal - BW). In its structure and its pharmacological actions it resembles bethanidine more than guanethidine.

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