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Sulphonamide mixtures - with penicillin and without

Abstract

PENICILLIN-SULPHONAMIDE MIXTURES - Numerous preparations containing a penicillin together with one or more sulphonamides have been available since the 1950s, but specialists concerned with the treatment of infections have never considered these mixtures important. In recent years they have been little advertised, and seemed to be heading for a quiet oblivion when fresh claims appeared for Penitriad (M & B) some months ago, advocating it ‘for common infections in general practice’, including boils, urinary infections, chronic bronchitis and prophylactic use in surgery and obstetrics. In our view the use of any penicillin-sulphonamide mixture for such purposes is inappropriate.

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