Peripheral neuropathy is a common long-term complication of diabetes mellitus. In many patients, neuropathy is accompanied by pain, which is often difficult to manage effectively. Drug treatment options include certain antidepressants and antiepileptic drugs. Another option is the use of topical capsaicin. In this article, we consider the evidence for capsaicin in the management of diabetic peripheral neuropathy and how it fits with current management strategies.
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