A freedom of information (FOI) request from DTB has sought to clarify why the recommended doses for Nystan (nystatin 100,000iu/mL oral suspension) for some age groups were substantially increased before reverting to their previous levels with no apparent explanation. Historically, the recommended nystatin dosage in the UK for all age groups (including children and adults) was 1mL four times/day.

In September 2015, in alignment with recommendations from a European public assessment report that …