RT Journal Article
SR Electronic
T1 Halothane and the liver
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 49
OP 51
DO 10.1136/dtb.13.13.49
VO 13
IS 13
YR 1975
UL http://dtb.bmj.com/content/13/13/49.abstract
AB It now seems likely that halothane can damage the liver in some patients, but how it does so remains undetermined. It has in particular been suggested that multiple exposure to halothane is hazardous and may lead to liver damage, often manifest as jaundice. The possible mechanisms of ‘halothane hepatitis’ have been debated at length but no clear consensus has yet emerged.1–3