RT Journal Article SR Electronic T1 Cimetidine JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 29 OP 32 DO 10.1136/dtb.17.8.29 VO 17 IS 8 YR 1979 UL http://dtb.bmj.com/content/17/8/29.abstract AB Cimetidine (Tagamet - SKF) is the first histamine-H2 receptor antagonist in general use. It reduces gastric acid secretion and is marketed for the treatment of duodenal ulcer, benign gastric ulcer, recurrent and stomal ulceration, reflux oesophagitis and Zollinger-Ellison syndrome.