PT  - JOURNAL ARTICLE
ED  - ,
TI  - Hydromet: methyldopa + hydrochlorothiazide
AID  - 10.1136/dtb.2.14.55
DP  - 1964 Jul 10
TA  - Drug and Therapeutics Bulletin
PG  - 55--56
VI  - 2
IP  - 14
4099  - http://dtb.bmj.com/content/2/14/55.short
4100  - http://dtb.bmj.com/content/2/14/55.full
SO  - Drug Ther Bull1964 Jul 10; 2
AB  - Hydromet (MSD) is a mixture of 250 mg methyldopa with 15 mg hydrochlorothiazide in a tablet offered for the treatment of hypertension. Both drugs may lower the blood pressure when it is raised. In a double-blind trial1 a combination of the two (given in separate tablets) was found to be better than either drug alone combined with a placebo. The dose of hydrochlorothiazide was 100 mg daily and the dose of methyldopa was increased from 1 to 2 G daily after the first week.