PT - JOURNAL ARTICLE ED - , TI - The artificial kidney and other methods of dialysis AID - 10.1136/dtb.3.19.73 DP - 1965 Sep 17 TA - Drug and Therapeutics Bulletin PG - 73--74 VI - 3 IP - 19 4099 - http://dtb.bmj.com/content/3/19/73.short 4100 - http://dtb.bmj.com/content/3/19/73.full SO - Drug Ther Bull1965 Sep 17; 3 AB - Renal failure results in the accumulation of substances normally excreted, e. g. creatinine, uric acid, urea, drugs and other unknown toxins. Fluid and electrolyte imbalance also occurs readily, most often leading to overhydration.