RT Journal Article SR Electronic T1 The artificial kidney and other methods of dialysis JF Drug and Therapeutics Bulletin JO Drug Ther Bull FD BMJ Publishing Group Ltd SP 73 OP 74 DO 10.1136/dtb.3.19.73 VO 3 IS 19 YR 1965 UL http://dtb.bmj.com/content/3/19/73.abstract AB Renal failure results in the accumulation of substances normally excreted, e. g. creatinine, uric acid, urea, drugs and other unknown toxins. Fluid and electrolyte imbalance also occurs readily, most often leading to overhydration.