PT - JOURNAL ARTICLE ED - , TI - ▾ Clozapine and ▾ loxapine for schizophrenia AID - 10.1136/dtb.29.11.41 DP - 1991 May 28 TA - Drug and Therapeutics Bulletin PG - 41--42 VI - 29 IP - 11 4099 - http://dtb.bmj.com/content/29/11/41.short 4100 - http://dtb.bmj.com/content/29/11/41.full SO - Drug Ther Bull1991 May 28; 29 AB - Clozapine (Clozaril – Sandoz) and loxapine (Loxapac – Lederle) are oral antipsychotic (neuroleptic) drugs recently marketed in Britain. Uniquely clozapine is licensed for the treatment of schizophrenic patients resistant to other drugs. The drug is claimed to improve both positive symptoms such as delusions and negative symptoms such as social withdrawal. Loxapine is a standard antipsychotic but is claimed to be of particular benefit in patients with paranoid schizophrenia.