PT - JOURNAL ARTICLE ED - , TI - â–¼Mirabegron for overactive bladder syndrome AID - 10.1136/dtb.2013.8.0196 DP - 2013 Aug 01 TA - Drug and Therapeutics Bulletin PG - 90--92 VI - 51 IP - 8 4099 - http://dtb.bmj.com/content/51/8/90.short 4100 - http://dtb.bmj.com/content/51/8/90.full SO - Drug Ther Bull2013 Aug 01; 51 AB - Urinary incontinence, the involuntary leakage of urine, can result from abnormalities of the urinary tract or may be caused by other conditions and is sub-divided into a number of classifications including stress incontinence and urge urinary incontinence.1 Urge urinary incontinence (UUI) is involuntary urine leakage accompanied by urgency of micturition.2 Overactive bladder (OAB) syndrome is defined as urgency occurring with or without UUI and usually occurs with frequency and nocturia.1 Wet OAB is associated with UUI, while dry OAB is not associated with incontinence. Current drug therapy for OAB involves the use of an antimuscarinic drug, of which there are a number available, such as oxybutynin, darifenacin, solifenacin and tolterodine.1,3 â–¼Mirabegron is the first of a new class of drug, beta-3-adrenoreceptor agonists, licensed for symptomatic treatment of urgency, increased micturition frequency and/or urgency incontinence as may occur in adult patients with OAB syndrome.4 Here we review the evidence for mirabegron.