TY - JOUR T1 - High-dose vitamin D for the prevention of RTI in young children JF - Drug and Therapeutics Bulletin JO - Drug Ther Bull SP - 111 LP - 111 DO - 10.1136/dtb.2017.10.0533 VL - 55 IS - 10 A2 - , Y1 - 2017/10/01 UR - http://dtb.bmj.com/content/55/10/111.1.abstract N2 - The effect of different doses of vitamin D for prevention of wintertime respiratory tract infections (RTI) in pre-school children has been assessed in a randomised trial.1 A recent meta-analysis of 25 trials in adults and children found that vitamin D had a modest effect of preventing acute RTIs among all participants (adjusted odds ratio 0.88, 95% CI 0.81 to 0.96; number-needed-to-treat 33), with a more pronounced effect in those with low vitamin D status (baseline circulating 25-hydroxyvitamin D … ER -