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Uses and dangers of vitamin K drugs


There is abundant evidence that phytomenadione (vitamin K1) is the only vitamin K preparation that rapidly corrects prothrombin deficiency in patients taking oral anticoagulants. Intravenous administration of vitamin K1 has however caused some serious reactions, including one death, and should be avoided when oral or intramuscular administration will serve.

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  • * Based on material published on December 6, 1963 in The Medical Letter, New York.