Abstract

Clotrimazole (Canesten - Bayer), an imidazole derivative was first synthesised in 1967.¹ It is active against many medically important fungi and yeasts and is available as a cream or as pessaries; an oral preparation is under trial. Care should be taken to distinguish clotrimazole from co-trimoxazole (Septrin - Burroughs Wellcome; Bactrim - Roche), a totally unrelated drug.