Abstract

Since the usefulness of topical corticosteroids in the treatment of ulcerative colitis was first reported¹ double-blind trials have confirmed their effectiveness, and they are now widely used.² For disease localised to the rectum suppositories, and for more extensive disease, retention enemas containing various corticosteroids are available (see table). In severe cases these preparations also valuably supplement systemic corticosteroid therapy, with or without sulphasalazine (Salazopyrin).