Article Text

Download PDFPDF
Interactions between phenytoin, phenobarbitone and other drugs


Many epileptic patients take more than one anticonvulsant drug. Interactions between these anticonvulsants and with other non-anticonvulsant medicaments are common.1 As with other drugs, interactions may occur at several sites, including absorption, plasma protein binding, biotransformation and excretion. We recently discussed the effects of anti-epileptic drugs on vitamin D, steroid and folate absorption and metabolism.2

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.