Article Text

Download PDFPDF
Peripheral vascular disease: cinnarizine et al


Peripheral vascular disease is common but its treatment is unsatisfactory. Generalised vasodilatation does not improve localised ischaemia.1 Other approaches that have been tried include changing the metabolism of ischaemic cells so that they can function better at the same oxygen tension, selectively dilating the vessels supplying the ischaemic zone, and altering the flow properties of the blood when these limit flow in the ischaemic area. Certainly a reduction in viscosity can produce clinical improvement.2

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.