Article Text

Download PDFPDF
Sympathomimetics in heart failure


The drug treatment of heart failure is changing. Diuretics remain the basic therapy, digoxin still has a place even in patients with sinus rhythm,1,2 but new agents are being used when these fail. They include inotropic agents which increase myocardial contractility, and vasodilator drugs which reduce either the load against which the heart has to work (after-load) by lowering peripheral resistance, or by reducing the central venous pressure (pre-load) by increasing venous compliance. In this article we discuss the sympathomimetic drugs dopamine, dobutamine, prenalterol, salbutamol, rimiterol and pirbuterol. These have inotropic and vasodilator (predominantly arteriolar) properties, or both.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.