Verapamil was the first calcium antagonist in clinical use and its value in the treatment of angina, hypertension and cardiac arrhythmias is well established.1 Standard verapamil tablets have to be taken twice or three times daily but now a scored sustained-release (s/r) tablet containing 240mg verapamil (Securon SR - Knoll) has been licensed for the treatment of mild to moderate hypertension. A single dose is claimed to lower blood pressure for 24 hours. As we have noted before,2 the pros and cons of s/r products need careful assessment.
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