Article Text

Download PDFPDF
Choosing between oral amoxycillin, pivampicillin and ampicillin


Amoxycillin and pivampicillin are both structural modifications of ampicillin. Amoxycillin is itself active but pivampicillin is a prodrug* which is hydrolysed to ampicillin in the body.1 Thus the antimicrobial spectrum and activity of pivampicillin and ampicillin are identical; those of amoxycillin differ little except in typhoid, where amoxycillin is better. Ampicillin is minimally more active than amoxycillin against Haemophilus influenzae.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • * Bacampicillin and talampicillin are other less used prodrugs of ampicillin.