Article Text

Download PDFPDF
Three new non-sedative antihistamines: worth keeping an eye open for


Oral antihistamines are used to relieve symptoms in allergic rhinitis, conjunctivitis, urticaria and eczema. Traditional H1 receptor antagonists have sedative, and in some cases anticholinergic, side effects. A significant advance has been the development of more specific H1 antagonists in which these other properties are greatly reduced. Terfenadine and astemizole were the first;1 acrivastine (Semprex - Wellcome), cetirizine (Zirtek - A&H) and loratadine (Clarityn - Schering Plough) are three newer ones. Are they better than terfenadine and astemizole?

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.