Article Text

Download PDFPDF
▾ Epoetin – an important advance


Erythropoietin is the endogenous hormone controlling red blood cell production. Most is made in the kidneys; if they fail, erythropoietin levels fall and anaemia develops. Treatment of erythropoietin deficiency anaemia in patients with renal failure has depended on repeated blood transfusions. Despite transfusions most patients remain anaemic and in addition are exposed to the risks of transfusion, such as viral infection, iron overload and problems associated with red cell antibody formation. The erythropoietin gene has been cloned and recombinant human erythropoietin (rHuEPO) is now marketed under the generic name epoetin. In this article we discuss the use of epoetin to treat anaemia in patients with renal failure and other potentially responsive conditions.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.