Abstract

Alprostadil, a prostaglandin, has been marketed for many years as a urethral stick and an intracavernous injection for the treatment of erectile dysfunction.¹ It is now available in the form of a cream (Vitaros—Takeda). Adverts for the product declare: “Sex with no pills, pellets or needles. Spot on.” In this article, we consider the evidence for alprostadil cream, and its place in the management of erectile dysfunction.