Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
A large systematic review and meta-analysis of observational studies has attempted to clarify whether medicines that suppress gastric acid increase the risk of recurrence of Clostridium difficile infection (CDI).1 Gastric acid suppression has been linked to both primary and recurrent CDI, but studies examining the association have found conflicting results. The US Food and Drug Administration (FDA) has issued a warning that proton pump inhibitors (PPIs) may be associated with an increased risk of C. difficile-associated diarrhoea.2 In 2013, Public Health England concluded that there was increasing evidence that acid-suppressing medications, including PPIs, may be a …