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Imagine you are one of the 65% of adults in the UK with multimorbidity. You will have several long-term conditions, including depression, and may be taking five or more medicines. There will be many visits to your general practice surgery each year: twice for the diabetes clinic with appointments for blood tests beforehand and another for retinal screening; appointments with the nurse for a chronic obstructive pulmonary disease review, a blood pressure check and influenza vaccination; and a handful of consultations with the GP to address depression and osteoarthritis. Most of these will be dealing with one problem at a time, following single-condition guidelines that may be based on evidence of limited applicability to you.1 You will make regular trips to the community pharmacy and may be offered an annual Medicines Use Review with the pharmacist. Being on the receiving end of all …