A community-based cohort study has attempted to clarify safety concerns surrounding metformin use in people with type 2 diabetes and chronic kidney disease (CKD).¹ In 2016, the USA Food and Drug Administration (FDA) changed the recommendations for metformin for diabetes to expand its use in certain patients with reduced kidney function.² However, despite this and other changes to metformin labelling, it was thought that many people may be missing out on the possible benefits of treatment with metformin because of persisting concerns over drug …