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The quadrivalent human papillomavirus (HPV4) vaccine has been shown to be over 99% effective at preventing pre-cancerous lesions associated with HPV.1 However, there have been case reports of autoimmune disorders and a (now retracted) news story in 2015 in Canada that was thought to have undermined confidence in the use of the vaccine.2 A large Canadian retrospective cohort study has sought to assess the risk of autoimmune disorders in girls after HPV4 vaccination.1
The study, which used the state of Ontario’s administrative health and vaccination databases from 2007 to …