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Review of: Medical and Healthcare products Regulatory Agency. SGLT2 inhibitors: reports of Fournier’s gangrene. Drug Safety Update 2019;12(7):3.
Key learning points
Necrotising fasciitis of the genitalia or perineum has been reported in people taking sodium-glucose co-transporter 2 (SGLT2) inhibitors for type 2 diabetes.
If gangrene is suspected, treatment with SGLT2 inhibitors should be stopped and treatment for gangrene (including antibiotics and surgical debridement) started immediately.
Urogenital infection or perineal abscess may precede necrotising fasciitis.
Prescribers and patients are …
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