From its first edition onwards, DTB has published assessments of therapeutic interventions to help doctors, pharmacists and nurses make informed and unbiased choices to help patients get the best care. Over the years, DTB has reviewed medicines, medical devices and drug delivery systems, as well as surgical, dietary and psychiatric interventions. Our reviews consider the quantity and quality of published data on efficacy, safety and cost-effectiveness, as well as practical aspects of the treatment that are likely to be important to patients. We believe that it is reasonable to expect that interventions are supported by high-quality evidence showing that they make a significant difference to patients. A DTB review provides readers with a balanced overview of …