Article Text

Download PDFPDF
Risperidone for rapid tranquilisation: more evidence required

Statistics from Altmetric.com

Review of: Ostinelli EG, Hussein M, Ahmed U, et al. Risperidone for psychosis-induced aggression or agitation (rapid tranquilisation). Cochrane Database of Syst Revs 2018;4: 10.1002/14651858.CD009412.pub2

Key learning points

  • This systematic review assessed whether oral risperidone alone is an effective treatment for psychosis‐induced aggression or agitation.

  • No studies reported on the primary outcome of tranquilisation within 30 min.

  • Very low-quality data for the main outcomes suggested no real effect for oral risperidone.

A lack of evidence for using oral risperidone for rapid tranquilisation has highlighted the need for more clinical trials evaluating oral antipsychotics in the emergency setting.1

Overview

This Cochrane review aimed to establish whether oral risperidone alone is an effective treatment for psychosis-induced aggression or agitation.1 Criteria for inclusion in the review included randomised …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.